• Minerva medica · Apr 1991

    [Hepatitis B and D recurrence after liver transplantation].

    • M Grendele, M Colledan, M Doglia, L R Fassati, G Ferla, B Gridelli, U Maggi, P Reggiani, G Rossi, and L Caccamo.
    • Ospedale Maggiore Policlinico, Milano.
    • Minerva Med. 1991 Apr 1; 82 (4): 151-61.

    AbstractIn Italy, many patients with B-virus (HBV) and Delta-virus (HDV) end-stage liver disease, are potential candidates to liver transplantation. Several authors have reported 70 to 100% hepatitis recurrence rates. From june 1983 to may 1989, 72 transplants on 60 patients were performed at Liver Transplantation Department of the Maggiore-Policlinico Hospital of Milan. The results in 26 HBsAg positive patients (19 with HDV infection), that underwent liver transplantation, are reported. A detailed report of 17 of these patients with a follow-up longer 7 months, and the clinical course of 4 patients with HBV reinfection, 3 of which had hepatitis recurrence, is also presented. The occurrence of HDV-RNA in the serum of 5 patients, that were negative for HBsAg and also other HBV-HDV replication markers after transplantation is discussed, together with the observation that in these patients no hepatitis recurrences or alteration of the clinical course were evident.

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