• J. Intern. Med. · May 2022

    Letter

    COVID-19 hospitalization is associated with pulmonary / diffusion abnormalities but not post-acute sequelae of COVID-19 severity.

    • Grace Y Lam, Dean Befus, Ronald W Damant, Giovanni Ferrara, Desi P Fuhr, Cheryl R Laratta, Angela Lau, Michael K Stickland, Rhea A Varughese, Eric Y Wong, and Maeve P Smith.
    • Division of Pulmonary Medicine, Department of Medicine, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada.
    • J. Intern. Med. 2022 May 1; 291 (5): 694-697.

    AbstractCoronavirus disease-19 (COVID-19) has resulted in much acute morbidity and mortality worldwide. There is now a growing recognition of the post-acute sequela of COVID-19, termed long COVID. However, the risk factors contributing to this condition remain unclear. Here, we address the growing controversy in the literature of whether hospitalization is a risk factor for long COVID. We found that hospitalization is associated with worse pulmonary restriction and reduction in diffusion capacity at 3 months post-infection. However, the impact on mental health, functional and quality of life is equally severe in those who have and have not been hospitalized during the acute infection. These findings suggest that hospitalization is a risk factor for pulmonary complications of long COVID but not the overall severity of long COVID.© 2021 The Association for the Publication of the Journal of Internal Medicine.

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