• Singap Med J · Jan 2015

    Review

    Interaction between warfarin and Chinese herbal medicines.

    • Yan Ting Chua, Xiang Ling Ang, Xi Ming Zhong, and Kei Siong Khoo.
    • Medical Oncology, Parkway Cancer Centre, 6A Napier Road, Gleneagles Hospital #01-35, Singapore 258500. khooks@pcc.sg.
    • Singap Med J. 2015 Jan 1; 56 (1): 111811-8.

    AbstractIn traditional Chinese medicine (TCM), the human body is divided into Yin and Yang. Diseases occur when the Yin and Yang balance is disrupted. Different herbs are used to restore this balance, achieving the goal of treatment. However, inherent difficulties in designing experimental trials have left much of TCM yet to be substantiated by science. Despite that, TCM not only remains a popular form of medical treatment among the Chinese, but is also gaining popularity in the West. This phenomenon has brought along with it increasing reports on herb-drug interactions, beckoning the attention of Western physicians, who will find it increasingly difficult to ignore the impact of TCM on Western therapies. This paper aims to facilitate the education of Western physicians on common Chinese herbs and raise awareness about potential interactions between these herbs and warfarin, a drug that is especially susceptible to herb-drug interactions due to its narrow therapeutic range.

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