• Hans J Welkoborsky, Susanne Pitz, Sylvia Grass, Boris Breuer, Anja Pähler Vor der Holte, Oliver Bertram, and Burkhard Wiechens.
• Department of Otorhinolaryngology, Head and Neck Surgery, Nordstadt Clinic, Academic Hospital, Hanover, Germany; Academic Medical Center, Interdisciplinary Orbita Center, Department of Ophthalmology, Hanover; Bürger Hospital, Orbita Center, Ophthalmic Clinic, Frankfurt/M Department for ENT Medicine, Center for; Children and Adolescents, Hanover; NordBlick Eye Clinic Bellevue, Kiel.
• Dtsch Arztebl Int. 2022 Jan 21; 119 (3): 313731-37.

BackgroundThe term "orbital complication" does not designate an independent nosological entity, but is rather a collective designation for diseases or disease effects that involve the orbit and its internal structures by extension from outside. In general, their most prominent manifestation is swelling of the orbital soft tissues, usually unilaterally. The incidence of sinogenic orbital complications is approximately 1.6 per 100 000 children and 0.1 per 100 000 adults per year.MethodsThis review is based on publications retrieved by a selective search of the literature on the epidemiology, diagnosis, and treatment of sinogenic orbital complications.ResultsAcute sinusitis is the most common cause of orbital complications. These are diseases of the orbit with potentially serious consequences for the eye and the risk of intracranial complications such as cavernous sinus thrombosis, meningitis, or brain abscess. Aside from acute sinusitis, many other infectious and non-infectious diseases can extend to and involve the orbit. Because of the complexity and severity of the condition, its diagnosis and treatment are always an interdisciplinary matter. The treatment is primarily conservative, under observation in a hospital, and generally consists of the treatment of acute sinusitis with measures to combat edema along with the administration of broad-spectrum antibiotics. Surgical intervention is needed in severe cases or if there is an abscess. An endonasal approach is usually used for drainage.ConclusionIn 95-98% of cases in stages I-IV, healing is complete and without further sequelae. Even if vision is affected preoperatively, it usually recovers fully when therapy is appropriate. Approximately 15% of the patients who undergo surgery need more than one operative procedure.

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