• Tayfun Birtay, Suzan Bahadir, Ebru Kabacaoglu, Ozgur Yetiz, Mehmet Fatih Demirci, and Gultekin Genctoy.
• From the Department of Anesthesia, Baskent University, Antalya, Turkey.
• Ann Saudi Med. 2021 Nov 1; 41 (6): 327-335.

BackgroundSARS-CoV2/COVID-19 emerged in China and caused a global pandemic in 2020. The mortality rate has been reported to be between 0% and 14.6% in all patients. In this study, we determined the clinical and laboratory parameters of COVID-19 related morbidity and mortality in our hospital.ObjectivesInvestigate the relationship between demographic, clinical, and laboratory parameters on COVID-19-related morbidity and mortality.DesignRetrospective observational study.SettingsTertiary care hospital.Patients And MethodsPatients diagnosed with COVID-19 pneumonia from March until the end of December were included in the study.Main Outcome MeasuresThe relationship between demographic, clinical, and laboratory parameters and the morbidity and mortality rates of patients diagnosed with COVID-19.Sample Size124 patients RESULTS: The mortality rate was 9.6% (12/124). Coronary artery disease (P<.0001) diabetes mellitus (P=.04) fever (>38.3°C) at presentation (P=.04) hypertension (P<.0001), and positive smoking history (P<.0001) were significantly associated with mortality. Patients who died were older, had a higher comorbid disease index, pneumonia severity index, fasting blood glucose, baseline serum creatinine, D-dimer, and had lower baseline haemoglobin, SaO2, percentage of lymphocyte counts and diastolic blood pressure. Patients admitted to the ICU were older, had a higher comorbidity disease index, pneumonia severity index, C-reactive protein, WBC, D-dimer, creatinine, number of antibiotics used, longer O2 support duration, lower hemoglobin, lymphocyte (%), and baseline SaO2 (%).ConclusionsOur results were consistent with much of the reported data. We suggest that the frequency, dosage, and duration of steroid treatment should be limited.LimitationsLow patient number, uncertain reason of mortality, no standard treatment regimen, limited treatment options, like ECMO.Conflict Of InterestNone.

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