Mathematical optimization of automated external defibrillator (AED) placement has demonstrated potential to improve survival of out-of-hospital cardiac arrest (OHCA). Existing models mostly aim to improve accessibility based on coverage radius and do not account for detailed impact of delayed defibrillation on survival. We aimed to predict OHCA survival based on time to defibrillation and developed an AED placement model to directly maximize the expected survival rate. ⋯ We developed a novel AED placement model based on the impact of time to defibrillation on OHCA outcomes. Mathematical optimization can improve OHCA survival.
Ahmad Reza Pourghaderi, Nikita Kogtikov, Michael H Lees, Wentong Cai, Pin PekPinPDepartment of Emergency Medicine, Singapore General Hospital, Singapore. Electronic address: maeve.pek@duke-nus.edu.sg., Fu ... more Wah HoAndrewAHealth Services and Systems Research, Duke-NUS Medical School, Singapore; Department of Emergency Medicine, Singapore General Hospital, Singapore., Ming NgWeiWEmergency Medicine Department, Ng Teng Fong General Hospital, Singapore. Electronic address: wei_ming_ng@nuhs.edu.sg., Jaeyoung Kwak, Elgin WhiteAlexanderAUnit for Prehospital Emergency Care, Ministry of Health, Singapore. Electronic address: alexander.elgin.white@upec.sg., Lynn LimShirSDepartment of Cardiology, National University Heart Centre Singapore, Singapore. Electronic address: mdclims@nus.edu.sg., Shao Wei LamSeanSHealth Services and Systems Research, Duke-NUS Medical School, Singapore; Health Services Research Centre, Singapore Health Services, Singapore. Electronic address: lam.shao.wei@singhealth.com.sg., and Eng Hock OngMarcusMHealth Services and Systems Research, Duke-NUS Medical School, Singapore; Health Services Research Centre, Singapore Health Services, Singapore; Department of Emergency Medicine, Singapore General Hospital, Singapore. Electronic address. less
Health Services and Systems Research, Duke-NUS Medical School, Singapore; Health Services Research Centre, Singapore Health Services, Singapore. Electronic address: pourghaderi@u.nus.edu.