• Tex Heart Inst J · Jan 2012

    Case Reports

    Metastatic carcinoid disease inducing coronary vasospasm.

    • Danny J Eapen, Stephen Clements, Peter Block, and Laurence Sperling.
    • Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30322, USA. deapen@emory.edu
    • Tex Heart Inst J. 2012 Jan 1; 39 (1): 76-8.

    AbstractHerein, we report a case of progressive coronary vasospasm in a 70-year-old man who had a long-standing history of metastatic gastrointestinal carcinoid tumor. Despite octreotide, nitrate, and calcium channel-blocker therapy, the patient's urinary 5-hydroxy-indole acetic acid level increased, coinciding with an increased frequency of flushing episodes with chest discomfort. In the cardiac catheterization laboratory, we captured an episode that was associated with diffuse right coronary artery spasm, ST-segment elevation, and intense symptoms. We attribute the patient's coronary vasospasm to his metastatic carcinoid disease.

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