• Feng-Chen Kao, Yun-Chi Chang, Tzu-Shan Chen, Ping-Hsin Liu, and Yuan-Kun Tu.
• Department of Orthopedics, E-Da Hospital, Kaohsiung, Taiwan.
• Medicine (Baltimore). 2021 Dec 10; 100 (49): e28053e28053.

AbstractThe purpose of the retrospective case-control study was to identify the causes of and risk factors for unplanned return to the operating room (uROR) within 24 hours in surgical patients.We examined 275 cases of 24-hour uROR in our hospital from January 2010 to December 2018. The reasons for 24-hour uROR were classified into several categories. Controls were randomly matched to cases in a 1:1 ratio with the selection criteria set for the same surgeon and operation code in the same corresponding year.The mortality rate was significantly higher in patients with 24-hour uROR (11.63% vs 5.23%). Bleeding was the most common etiology (172/275; 62.55%) and technical error (14.5%) also contributed to 24-hour uROR. The clinical factors that led to bleeding included a history of liver disease (P = .032), smoking (P = .002), low platelet count in preoperative screening (P = .012), and preoperative administration of antiplatelet or anticoagulant agents (P = .014).Clinicians should recognize the risk factors for bleeding and minimize errors to avoid the increase in patient morbidity and mortality that is associated with 24-hour uROR.Level of Evidence: Level IV.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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