• Chang-Cheng Dong, Xue-Jun Jiang, Xue-Ying Shi, Bing Li, and Liang Chen.
• Department of General Surgery, Inner Mongolia Baogang Hospital (The Third Affiliated Hospital of Inner Mongolia Medical University), Kundulun District, Baotou, Inner Mongolia Autonomous Region, China.
• Medicine (Baltimore). 2021 Dec 10; 100 (49): e28191e28191.

BackgroundBile duct injury (BDI) is one of the serious complications in laparoscopic cholecystectomy (LC), but there is currently a lack of systematic review of risk factors related to BDI after LC. This study conducts meta-analysis on the risk factors related to bile duct injury after LC, the purpose is to provide reference basis for preventing and reducing BDI after LC.MethodsUsing the Computer to retrieve of Chinese and English databases such as CNKI, WANFANG Data, the VIP Network, PubMed, Embase, the Cochrane Library, etc. The time is from the establishment of each database until August 2021. A case-control study is selected that is related to the risk factors of BDI after LC. This meta-analysis using RevMan 5.4 and State 12.0 software is performed after two researchers independently sift through the literature, extract the data, and evaluate the bias risk included in the study.ResultsThe risk factors related to BDI after LC will be analyzed by systematic review.ConclusionThe conclusion of this study will play an important role in reducing BDI after LC.Osf RegistrationDOI 10.17605/OSF.IO/2B3K9, the registration URL is https://osf.io/2b3k9.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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