• Arch. Dis. Child. Fetal Neonatal Ed. · Jul 2021

    Randomized Controlled Trial

    Randomised study of heart rate measurement in preterm newborns with ECG plus pulse oximetry versus oximetry alone.

    • Madeleine C Murphy, Allan Jenkinson, John Coveney, Lisa K McCarthy, and Colm Patrick Finbarr O Donnell.
    • Department of Neonatology, National Maternity Hospital, Dublin, Ireland.
    • Arch. Dis. Child. Fetal Neonatal Ed. 2021 Jul 1; 106 (4): 438-441.

    AimTo determine whether the IntelliVue monitor (ECG plus Masimo pulse oximeter (PO)) displays heart rate (HR) at birth more quickly than Nellcor PO (PO alone) among infants of 29-35 weeks' gestational age.MethodsUnmasked parallel group randomised (1:1) study.ResultsWe planned to enrol 100 infants; however, the study was terminated due to the COVID-19 pandemic when 39 infants had been enrolled (17 randomised to IntelliVue, 22 to Nellcor). We found no differences between the groups in the time to first HR display (median (IQR) IntelliVue ECG 49 (33, 71) vs Nellcor 47 (37, 86) s, p>0.999), in the proportion who had a face mask applied for breathing support, or in the time at which it was applied. Infants monitored with IntelliVue were handled more frequently and for longer.ConclusionIntelliVue ECG did not display HR more quickly than Nellcor PO in preterm infants. We found no differences in the rate of or time to intervention between groups. Our study was terminated early so these findings should be interpreted with caution.Trial Registration NumberISRCTN16473881.© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

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