• Emilie Karafillakis, Clarissa Simas, Caitlin Jarrett, Pierre Verger, Patrick Peretti-Watel, Fadia Dib, Stefania De Angelis, Judit Takacs, Karam Adel Ali, Pastore CelentanoLuciaLk Vaccine Preventable Disease Programme, European Centre for Disease Prevention and Control , Stockholm , Sweden., and Heidi Larson.
• a Department of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine (LSHTM) , London , UK.
• Hum Vaccin Immunother. 2019 Jan 1; 15 (7-8): 1615-1627.

AbstractEurope is increasingly described as the region in the world with the least confidence in vaccination, and particularly in the safety of vaccines. The aim of this systematic literature review was to gather and summarise all peer-reviewed and grey literature published about determinants of Human Papillomavirus (HPV) vaccine hesitancy in Europe. Ten thematic categories were identified across the 103 articles which were included in the review. Participants from European studies most commonly reported issues with the quantity and quality of information available about HPV vaccination; followed by concerns about potential side effects of the vaccine; and mistrust of health authorities, healthcare workers, and new vaccines. Comparative analyses indicated that confidence determinants differed by country and population groups. This evidence supports the need to develop context-specific interventions to improve confidence in HPV vaccination and design community engagement strategies aiming to build public trust.

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