• Critical care medicine · Oct 2002

    Case Reports

    Floating aortic thrombus in systemic aspergillosis and detection by transesophageal echocardiography.

    • Frank Grothues, Tobias Welte, Hans J Grote, Albert Roessner, and Helmut U Klein.
    • Department of Cardiology, Angiology and Pneumology, Otto von Guericke University Magdeburg, Germany.
    • Crit. Care Med. 2002 Oct 1; 30 (10): 2355-8.

    AbstractAfter immunosuppressive treatment for a colitis ulcerosa, a 49-yr-old man developed signs of systemic aspergillosis with subsequent septic shock and encephalitis. For recurrent signs of thromboembolism, transesophageal echocardiography was performed and revealed a large floating thrombus of the aortic arch. Despite appropriate antibiotic treatment, the patient died a few days later suffering from adult respiratory distress syndrome. The appearance of aortic thrombi concomitant to systemic fungal infection rarely has been reported. The present case is the first report of in vivo detection of large vessel involvement in systemic aspergillosis by transesophageal echocardiography. In our opinion, transesophageal echocardiography is the method of choice for bedside diagnosis of this rare complication in critically ill patients.

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