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- A Elati and A D Weeks.
- School of Reproductive and Developmental Medicine, University of Liverpool, Liverpool, UK. aweeks@liverpool.ac.uk
- BJOG. 2009 Oct 1; 116 Suppl 1: 61-9.
AbstractMisoprostol, although originally introduced as a therapy for gastric ulcers, is now widely used in reproductive health. For some indications it is now the optimal choice, whilst for others it provides an important alternative, especially in low-resource settings. The optimal dose varies widely from 20 to 600 mcg depending on the indication and gestation. Use of the correct dose is important, too low a dose will be ineffective and overdosage can be dangerous for mother and baby. Evidence-based information about the safest regimens for multiple pregnancy indications are therefore provided in this review.
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