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Case Reports
Hereditary Antithrombin Deficiency: A Balancing Act of Perioperative Hemostasis and Thromboprophylaxis-A Case Report.
- Kofi VanDyck, Ian F Dunn, Cooper Yates, Christopher Robbs, and Kenichi A Tanaka.
- From the Departments of Anesthesiology.
- A A Pract. 2021 Dec 17; 15 (12): e01550.
AbstractHereditary deficiency of antithrombin (AT) is associated with increased risk of venous thromboembolism (VTE), especially under the circumstances of stress, vascular injury, and immobilization associated with surgery. To date, there is no consensus on the use of perioperative anticoagulant bridging in the setting of hereditary thrombophilia. Balancing hemorrhagic and thrombotic risks associated with anticoagulant bridging and AT deficiency can be challenging to perioperative physicians. We present a case of a 65-year-old woman with inherited AT deficiency with history of multiple VTEs who was admitted for presurgical anticoagulant bridging before microvascular decompression craniotomy for trigeminal neuralgia.Copyright © 2021 International Anesthesia Research Society.
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