• Dalila Scaturro, Maria Grazia Benedetti, Giulia Lomonaco, Sofia Tomasello, Maria Grazia Giuseppina Farella, Giuseppina Passantino, Antonio Frizziero, and Giulia Letizia Mauro.
• Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo Rehabilitation Unit, Paolo Giaccone Hospital, Palermo, Italy.
• Medicine (Baltimore). 2021 Dec 17; 100 (50): e27863e27863.

IntroductionLiterature provides unclear evidence of the effectiveness of many physiotherapy interventions on pain intensity, quality of life, and functional ability in hemophilic patients, and suggests that rehabilitation programs should be focused on functional goals and the disability of patients.AimThe aim of the present study is to present the outcome of a case series of patients with hemophilia in which a rehabilitation program has been carried out on the basis of a specific individual patient's functional impairment.MethodsFifty-one patients were enrolled: 32 patients (Rehab Group) received a rehabilitative treatment, 19 patients for different reasons (living far from the hospital, family problems) did not receive rehabilitation (Control Group). The rehabilitation program was planned with respect to the emergent problems: musculoskeletal pain, joint range of motion limitation, muscle flexibility, walking difficulties, the appearance of hematomas/hemartro, and postural problems. All the patients were assessed at baseline (T0), after 1 month (T1), and after 3 months (T2) through visual analogic scale for musculoskeletal pain, the Hemophilia Joint Health Score for joint range of motion, the Functional Independence Score in Hemophilia for disability, and postural assessment by visual inspection.ResultsA significant reduction of pain and improvement of Hemophilia Joint Health Score and Functional Independence Score in Hemophilia score was found in the Rehab Group along with the follow-up. Pain in the Control Group was lower with respect to the other group at baseline and significantly decreased after 1 month.ConclusionA rehabilitation program focused on individual impairment of patients with hemophylia determined satisfying results in terms of pain control, functional, and disability improvement in 3 months follow-up.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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