• Huabin Lei, Wei Wang, Yinan Cao, Yaru Ma, and Xusheng Xue.
• Sun Simiao Hospital, Beijing University of Chinese Medicine, Tongchuan, Shaanxi, China.
• Medicine (Baltimore). 2021 Dec 17; 100 (50): e27937.

BackgroundPost-stroke insomnia (PSI) is a common and severe illness among the complications of stroke. Although there are plenty of drugs currently used for PSI treatment, they generate several side effects and other problems. Bright light therapy (BLT) is thought to be relatively safe and effective in treating PSI patients. Despite this, there is still a lack of systematic review on BLT in the treatment of PSI. Allowing for this, the aim of this study is to assess the efficacy and safety of BLT for PSI.MethodsThe meta-analysis and systematic review will perform a comprehensive electronic search for items fulfilling the required criteria in Web of Science, Google Scholar, Wan Fang database, MEDLINE, Baidu Scholar, PubMed, SinoMed, Embase, Chinese Biomedical Literature Database (CBM), China national knowledge infrastructure database (CNKI), Cochrane Library Central Register of Controlled Trials (CENTRAL), and Wei Pu database from establishment to January 1, 2022. We will select articles, collect data, and assess the methodology quality. And we will set the primary outcome and secondary outcomes in this research. RevMan 5.3 software will be used to analyze the data for this investigation.ResultsThe work of this research will be published in peer-reviewed scientific journals.ConclusionThe aim of this study is to assess the efficacy and safety of BLT for PSI and present robust scientific evidence concerning BLT for PSI.RegistrationINPLASY2021100065.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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