• Medicina · Jan 2004

    Review Comparative Study

    [Ibogaine--the substance for treatment of toxicomania. Neurochemical and pharmacological action].

    • Saulius Kazlauskas, Violeta Kontrimaviciūte, and Audrius Sveikata.
    • Department of Analytical and Toxicological Chemistry, Kaunas University of Medicine, Kaunas, Lithuania. saulius_kazlauskas@gama.vtu.lt
    • Medicina (Kaunas). 2004 Jan 1; 40 (3): 216-9.

    AbstractThe review of scientific literature, concerning the indol alkaloid Ibogaine, which is extracted from the bush Tabernanthe Iboga, is presented in this article. Used as a stimulating factor for hundred of years in non-traditional medicine, this alkaloid could be important for modern pharmacology because of potential anti-addictive properties. The mechanism of action of this alkaloid is closely related to different neurotransmitting systems. Studies with animals allow concluding that Ibogaine or medicines based on this alkaloid can be used for treatment of drug dependencies.

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