• Hui Jin, Yao Gao, Youbo Ji, Rui Xu, Hao Zuo, and Zhonghan Wang.
• Department of Pain, The Second Hospital of Jilin University, Changchun, PR China.
• Medicine (Baltimore). 2021 Dec 23; 100 (51): e27797.

RationaleThe shoulder joint is the most movable joint of the human body, and the incidence of aseptic inflammation of the muscles and tendons around the shoulder joint and acute and chronic muscle injuries is relatively high. Pulsed radiofrequency neuromodulation technology is gradually being used in shoulder joint diseases. Platelet-rich plasma (PRP) is a high-power platelet plasma solution obtained by centrifugation of autologous blood. Platelet cells contain many growth factors that promote tissue repair.Patient ConcernsShoulder soreness, limited movement of the shoulder joint, abduction of the upper limbs, and aggravation of pain during flat lifting. The pain radiates to the deltoid muscle stop and forearm.InterventionsIn this study, radiofrequency pulses combined with PRP were used to treat supraspinatus muscle injury and explore new methods for the treatment of shoulder joint muscle and tendon injuries represented by supraspinatus muscle injury.DiagnosisWe reported 4 patients with supraspinatus injury who received radiofrequency pulse combined with PRP treatment in our hospital.OutcomesAfter treatment, the patients were followed up at the first month, the third month, and the sixth month, and the Constant-Murley shoulder score and visual analog scale were used to comprehensively evaluate the postoperative improvement of the patients. There was no significant increase in postoperative pain, the Constant-Murley shoulder Score was significantly increased, the range of movement of the shoulder joint was significantly improved, and there were no postoperative complications.LessonsThe combined application of the 2 treatments can make full use of the analgesic effect of pulsed radiofrequency technology and the repairing effect of PRP, and can maximize the advantages of the 2 more advanced treatment methods in the field of minimally invasive.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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