• Bettina Grüne, Sophie Meesters, Claudia Bausewein, and Eva Schildmann.
• Department of Palliative Medicine (B.G., S.M., C.B., E.S.), University Hospital, LMU Munich, Germany; German Youth Institute (DJI), Department of Youth and Youth Services (B.G.), Munich, Germany. Electronic address: bettina.gruene@med.uni-muenchen.de.
• J Pain Symptom Manage. 2022 Apr 1; 63 (4): 530-538.

ContextSedation is an accepted, but controversially discussed and challenging measure to treat suffering at the end of life. Although most people die in hospitals or nursing homes, little is known how professionals in these settings deal with sedatives and sedation at the end of life.ObjectivesTo explore 1) challenges regarding use of sedatives and sedation at the end of life in hospitals and nursing homes, and 2) strategies, and supportive measures to meet these challenges, as perceived by nurses and physicians.MethodsMulticenter qualitative interview study. Forty-nine participants: 12 general practitioners and 12 nurses from five nursing homes, 12 physicians, and 13 nurses from five hospital departments (hematology/oncology (n = 2), neurology, geriatrics, gynecology). Semi-structured qualitative interviews. Data analysis guided by framework approach.ResultsPerceived challenges relate to three levels of the care situation: individual, interaction with others, and work environment. The main challenge was defining the adequate timing and/or dose. Other challenges, e.g., disagreements regarding indication or legal uncertainties, were highly interrelated, and strongly associated with this major challenge. Reported strategies and supportive measures to address challenges also corresponded to the three interrelated levels. Major named strategies were education and training, joint decision-making within the team and regular discussion with the patient and family. On the level work environment, no implemented strategies, but wishes for change were identified.ConclusionTo meet the identified challenges in a sustainable way and enable continuous improvement of quality of care, best practice recommendations, and other supportive measures have to address all identified levels of challenges.Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

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