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Internal medicine journal · Jun 2022
ReviewPlatypnoea-Orthodeoxia Syndrome as an Uncommon Cause of Dyspnoea: a Literature Review.
- Marco Lombardi, Marco G Del Buono, Giuseppe Princi, Gabriella Locorotondo, Antonella Lombardo, Rocco Vergallo, Rocco A Montone, Francesco Burzotta, Carlo Trani, Filippo Crea, and Tommaso Sanna.
- Department of Cardiovascular Sciences, Catholic University of the Sacred Heart, Rome, Italy.
- Intern Med J. 2022 Jun 1; 52 (6): 921-925.
AbstractPlatypnoea-orthodeoxia syndrome (POS) is an uncommon but challenging clinical condition characterised by positional dyspnoea (platypnoea) and arterial desaturation (orthodeoxia) in the upright position that improve in the supine position. Since its first description, many cases have been reported and many conditions have been associated with this syndrome. Herein, we review the clinical presentation, pathophysiology, diagnostic work-up and management of patients with POS, aiming to increase the awareness of this often misdiagnosed condition.© 2021 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.
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