• Internal medicine journal · Nov 2021

    Consensus guidelines for the diagnosis and management of cryptococcosis and rare yeast infections in the haematology/oncology setting, 2021.

    • Christina C Chang, Victoria Hall, Celia Cooper, George Grigoriadis, Justin Beardsley, Tania C Sorrell, Christopher H Heath, and and the Australasian Antifungal Guidelines Steering Committee.
    • Department of Infectious Diseases, Alfred Hospital and Central Clinical School, Monash University, Melbourne, Victoria, Australia.
    • Intern Med J. 2021 Nov 1; 51 Suppl 7: 118-142.

    AbstractCryptococcosis caused by the Cryptococcus neoformans-Cryptococcus gattii complex is an important opportunistic infection in people with immunodeficiency, including in the haematology/oncology setting. This may manifest clinically as cryptococcal meningitis or pulmonary cryptococcosis, or be detected incidentally by cryptococcal antigenemia, a positive sputum culture or radiological imaging. Non-Candida, non-Cryptococcus spp. rare yeast fungaemia are increasingly common in this population. These consensus guidelines aim to provide clinicians working in the Australian and New Zealand haematology/oncology setting with clear guiding principles and practical recommendations for the management of cryptococcosis, while also highlighting important and emerging rare yeast infections and their recommended management.© 2021 Royal Australasian College of Physicians.

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