• Sâmara Paula Ferreira Mota Colares, Guilherme Moura Colares, Freire de CarvalhoJozélioJInstitute for Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil., and Ewerton Maia RodriguesCarlosCUniversity of Fortaleza (Unifor), Fortaleza, Brazil.Federal University of Ceará, Fortaleza, Brazil..
• University of Fortaleza (Unifor), Fortaleza, Brazil.
• Isr Med Assoc J. 2021 Dec 1; 23 (12): 766-772.

BackgroundLumbar spinal stenosis (LSS) is a narrowing of the lumbar canal causing lower back pain, gluteal pain, and neurogenic claudication. LSS has been associated with cardiovascular co-morbidities. Metabolic syndrome (MetS), a pro-inflammatory condition involving a cluster of risk factors for cardiovascular disease and diabetes, is increasingly prevalent worldwide.ObjectivesTo evaluate the prevalence of MetS in patients with LSS, compared to age- and sex-matched healthy controls, and to explore potential associations between MetS and LSS-related clinical parameters and cardiovascular risk factors.MethodsWe conducted a cross-sectional study including 64 patients diagnosed as symptomatic LSS (NASS criteria) and 32 controls. MetS was diagnosed using the 2009 Harmonizing criteria adjusted for South Americans. Multivariate logistic regression was used to identify independent risk factors for MetS. The level of statistical significance was set at 5.ResultsThe prevalence of MetS was significantly higher in the LSS group than in the control group (76.6% vs. 31.3%; P < 0.001). LSS patients displayed greater waist circumference (P = 0.003), blood glucose levels (P = 0.009) and arterial pressure (P < 0.001) than controls. The variables with independent influence on MetS in the logistic regression model were: diabetes (P = 0.008), blood glucose (P = 0.004), and body mass index (P = 0.005).ConclusionsMetS was significantly more prevalent among LSS patients, and diabetes and elevated body mass index were found to be risk factors for MetS in these LSS patients.

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