• Huixin Yan, Yun An, Tao Zhang, Jiangna Zhao, and Juntao Yan.
• Department of Tuina, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, P.R. China.
• Medicine (Baltimore). 2021 Nov 24; 100 (47): e27964e27964.

BackgroundDiabetic gastroparesis (DGP) is one of the most common complication of diabetes. At present, despite the increasing number of clinical researches of treatment with Tuina have been reported, there are no systematic reviews of Tuina therapy for DGP. Therefore, it is of great significance to evaluate its safety and efficacy as a complementary and alternative therapy.Methods And AnalysisRandomized controlled trials (RCTs) of Tuina therapy in the treatment of DGP will be retrieved from PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wan Fang Database (Wan Fang), Chinese Biomedical Literature Database (CBM), VIP Database for Chinese Technical Periodicals (VIP), Medline, and Clinical Trial Register (CTR). We will consider articles published in English or Chinese between database initiation and October 2021. Research selection, data extraction, risk of bias assessment, and meta-analyses will be independently completed by 2 researchers. Our researchers will use Revman 5.3 software, provided by the Cochrane Collaborative Network for conducting systematic reviews and meta-analysis.ResultsThis systematic review provides a high-quality synthesis to assess the effectiveness and safety of Tuina therapy for treating DGP.ConclusionThe conclusions of our study will provide evidence to determine whether Tuina therapy is an effective and safe intervention for patients with DGP.Systematic Review Registration: INPLASY2021110019.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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