• Int. J. Infect. Dis. · Mar 2021

    Case Reports

    Persistent replication of SARS-CoV-2 in a severely immunocompromised patient treated with several courses of remdesivir.

    • Daniel Camprubí, Anna Gaya, Maria Angeles Marcos, Helena Martí-Soler, Alex Soriano, Maria Del Mar Mosquera, Aina Oliver, Marta Santos, Jose Muñoz, and Carol García-Vidal.
    • Barcelona Institute for Global Health (ISGlobal) Hospital Clínic - Universitat de Barcelona, Barcelona, Spain. Electronic address: dcamprub@clinic.cat.
    • Int. J. Infect. Dis. 2021 Mar 1; 104: 379-381.

    AbstractMicrobiological response of SARS-CoV-2 to remdesivir in immunocompromised patients has not been evaluated. We present the case of a severely immunocompromised patient with persistent replication of SARS-CoV-2, who required different courses of remdesivir. Short courses of remdesivir might be insufficient in immunocompromised patients due to prolonged viral clearance.Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved.

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