• Crit Care Explor · Sep 2021

    Argatroban for Anticoagulation in Patients Requiring Venovenous Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019.

    • Lauren A Sattler, Joshua M Boster, Kelly M Ivins-O'Keefe, Michal J Sobieszczyk, Bradley A Reel, Phillip E Mason, Robert J Walter, and Valerie G Sams.
    • Internal Medicine Service, Department of Medicine, Brooke Army Medical Center, San Antonio, TX.
    • Crit Care Explor. 2021 Sep 1; 3 (9): e0530.

    AbstractA significant proportion of patients with coronavirus disease 2019 requiring venovenous extracorporeal membrane oxygenation at our institution demonstrated heparin resistance, which in combination with a heparin shortage resulted in the transition to argatroban with or without aspirin as an alternative anticoagulation strategy. The optimal anticoagulation strategy for coronavirus disease 2019 patients requiring venovenous extracorporeal membrane oxygenation is unknown, and therefore, we sought to evaluate the efficacy and safety of argatroban with or without aspirin as an alternative anticoagulation strategy in this patient population.Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

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