• J Clin Neurosci · Feb 2011

    Case Reports

    Hemichorea-hemiballismus in non-ketotic hyperglycaemia.

    • H Cheema, D Federman, and A Kam.
    • Department of Radiology, Alfred Hospital, Commercial Road, Prahran, Victoria 3181, Australia. h.cheema@alfred.org.au
    • J Clin Neurosci. 2011 Feb 1; 18 (2): 293-4.

    AbstractHemichorea-hemiballismus is a rare complication of nonketotic hyperglycaemia in type 2 diabetes. It is associated with contralateral striatal radiological abnormality, most typically T1 hyperintensity on MRI. We report a case of a 91 year old woman who presented in a nonketotic hyperglycaemic state with right sided hemichorea. Brain CT revealed hyperdensity of the left lentiform nucleus and MRI 15 days post presentation showed left lentiform T1 hyperintensity and enlargement. The chorea improved after control of blood glucose levels. The pathophysiology of this syndrome remains controversial. It is likely that a combination of hyerglycaemia induced basal ganglia metabolic derangement and failure of cerebral blood flow autoregulation contribute to the syndrome.Copyright © 2010 Elsevier Ltd. All rights reserved.

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