• Semin. Pediatr. Surg. · Jun 2017

    Review

    Fetal imaging and therapy for CDH-Current status.

    • Titilayo Oluyomi-Obi, Tim Van Mieghem, and Greg Ryan.
    • Section of Maternal Fetal Medicine, Department of Obstetrics and Gynaecology, University of Calgary, 1403 29 Street NW, Calgary, Alberta. Electronic address: titilayo.oluyomi@ahs.ca.
    • Semin. Pediatr. Surg. 2017 Jun 1; 26 (3): 140-146.

    AbstractIn congenital diaphragmatic hernia (CDH), herniation of the abdominal organs into the fetal chest causes pulmonary hypoplasia and pulmonary hypertension, the main causes of neonatal mortality. As antenatal ultrasound screening improves, the risk of postnatal death can now be better predicted, allowing for the identification of fetuses that might most benefit from a prenatal intervention. Fetoscopic tracheal occlusion is being evaluated in a large international randomized controlled trial. We present the antenatal imaging approaches that can help identify fetuses that might benefit from antenatal therapy, and review the evolution of fetal surgery for CDH to date.Copyright © 2017 Elsevier Inc. All rights reserved.

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