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Cancer investigation · Aug 2009
Cutaneous human papillomavirus in head and neck squamous cell carcinomas.
- Katja Lindel, Burkhard Helmke, Christian Simon, Klaus J Weber, Juergen Debus, and Ethel-Michele de Villiers.
- Department of Radiation Oncology and Radiotherapy, University of Heidelberg, Heidelberg, Germany. Katja Lindel@med.uni-heidelberg.de
- Cancer Invest. 2009 Aug 1; 27 (7): 781-7.
AbstractTo evaluate the prevalence and meaning of cutaneous human papillomavirus (HPV) types in HNSCC 51 patients were analyzed for the prevalence of cutaneous as well as mucosal HPV. HPV DNA was demonstrated in 18 (35%) of 51 tumors. The majority of these HPV types belong to so-called cutaneous HPV types, whereas only HPV 6 and HPV 16 were from the mucosal HPV types. A possible role for cutaneous HPV types as co-factors in the oncogenesis of HNSCC remains to be elucidated and may be relevant for future strategies of cancer prevention.
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