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Kidney international · Nov 2006
CommentBisphosphonates prevent experimental vascular calcification: Treat the bone to cure the vessels?
- V Persy, M De Broe, and M Ketteler.
- Department of Pathophysiology, University of Antwerp, Antwerp, Belgium. veerle.persy@ua.ac.be
- Kidney Int. 2006 Nov 1; 70 (9): 1537-8.
AbstractBisphosphonates are inhibitors of bone resorption that are widely used to treat osteoporosis. Price and colleagues demonstrate that ibandronate suppressed the development of uremia-related vascular calcification in rats. These findings extend the link between bone remodeling and vascular calcification to the context of chronic renal failure, opening perspectives toward novel therapeutic strategies.
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