• Int. J. Cardiol. · Nov 2008

    Letter Case Reports

    In-stent restenosis and thrombosis 41 months after drug-eluting stent implantation.

    • Peiman Jamshidi, Stefan Toggweiler, and Paul Erne.
    • Int. J. Cardiol. 2008 Nov 28; 130 (3): e111-3.

    AbstractEvidence indicates that very late stent thrombosis (>1 year) occurs more frequently in drug-eluting stents than in bare metal stents after discontinuation of clopidogrel. We present a case of an 83 year old man with an LAD in-stent thrombosis 41 months after stenting with a sirolimus-eluting stent in whom clopidogrel was discontinued after 6 months based on these days' guidelines. In-stent thrombus was aspirated and intracoronary ultrasound (ICUS) showed significant in-stent restenosis which had narrowed the minimal lumen diameter by 1 mm. The lesion was stented with a bare metal stent. The patient was discharged after recovery and had no recurrence of stent thrombosis in one month follow-up. We recommended indefinite dual antiplatelet therapy with aspirin and clopidogrel.

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