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- Christophe Kosinski, Christel Tran, Thierry Kuntzer, Nicolas Rodondi, and Tinh-Hai Collet.
- Consultation spécialisée des lipides, Service d'endocrinologie, diabétologie et métabolisme, CHUV, Avenue de la Sallaz 8, 1011 Lausanne.
- Rev Med Suisse. 2018 Feb 28; 14 (596): 462-469.
AbstractStatins are the first line treatment in hyperlipidemia, either in primary or secondary prevention of cardiovascular diseases. One of the most prescribed drug class worldwide, this drug class is often the focus of highly publicized drug controversies. Various adverse effects have been attributed to statins, in particular statin-associated muscle symptoms (SAMS). This condition varies in severity (from frequent isolated myalgia to rare severe myositis, even rhabdomyolysis) and often leads to treatment termination. Because SAMS are a daily challenge in clinical practice, we review here the recent medical literature on this topic and suggest a management strategy to be shared with the patient as an active partner.
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