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Review Case Reports
Positive apraclonidine test 36 hours after acute onset of horner syndrome in dorsolateral pontomedullary stroke.
- Maud Lebas, Julien Seror, and Thomas Debroucker.
- Department of Ophthalmology, Hôpital Delafontaine, Saint-Denis, France. maudjacob@gmail.com
- J Neuroophthalmol. 2010 Mar 1; 30 (1): 12-7.
AbstractA 40-year-old man developed a Horner syndrome as part of a dorsolateral medullary brainstem infarction. Thirty-six hours after the onset of the stroke, topical instillation of 0.5% apraclonidine produced reversal of anisocoria. This is the first case in which apraclonidine testing has been applied to a patient with a Horner syndrome caused by a lesion in the first segment of the oculosympathetic pathway and the shortest reported interval between clinical manifestations of the lesion and apraclonidine-induced reversal of anisocoria. A review of all reported cases of apraclonidine testing in Horner syndrome suggests that this is a promising diagnostic adjunct that must be validated in larger studies.
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