• M M McDermott, F Lefevre, M Arron, J Foley, G J Martin, and J Biller.
• Division of General Internal Medicine, Chicago, IL, U.S.A.; Northwestern University Medical School, Chicago, IL, U.S.A.
• J Stroke Cerebrovasc Dis. 1995 Jan 1; 5 (3): 180-4.

AbstractPatients with a history of ischemic stroke or transient ischemic attack (TIA) are at significant risk of cardiac death. This study reports the prognostic significance of ST-segment depression and ventricular tachycardia on continuous electrocardiography in 48 consecutive patients hospitalized with an acute ischemic stroke or TIA. Thirty-one percent of patients had episodes of asymptomatic ST-segment depression and 6% had transient ventricular tachycardia on continuous electrocardiographic monitoring. At a mean follow-up of 13 months, 19% had experienced a cardiac outcome, and 19% met criteria for a neurologic outcome. Cardiac and neurologic outcomes, including death, were not significantly different in patients with and without ST-segment depression on continuous electrocardiography. Cardiac outcomes occurred in 13% of patients with ST-segment depression and in 21% of patient without ST-segment depression (p = 0.52). However, ventricular tachycardia was associated with a higher rate of cardiac death (33% vs. 2%, p < 0.01). Only 27% of patients subsequently found to have coronary artery disease had ST-segment depression by continuous electrocardiography. In contrast to patients with coronary artery disease, ST-segment depression on continuous electrocardiography is not associated with poorer outcome among patients with acute ischemic stroke or TIA. Copyright © 1995 National Stroke Association. Published by Elsevier Inc. All rights reserved.

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