• Hyejin Mo, Juhan Lee, Jae Berm Park, Sun Cheol Park, KimYoung HoonYHhttps://orcid.org/0000-0003-3840-8426Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Ahram Han, In Mok Jung, Jongwon Ha, Nam-Joong Kim, and Sangil Min.
• Department of Surgery, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
• J. Korean Med. Sci. 2022 Jan 3; 37 (1): e4.

BackgroundThe use of organs from donors with infection is limited because of the possibility of transmission. We aimed to investigate the transmission after deceased donor transplantation with bloodstream infection (BSI).MethodsA retrospective study of patients undergoing kidney or pancreas transplantation at five tertiary centers in Korea from January 2009 and November 2019 was performed. We analyzed the outcomes after transplantation from deceased donors with BSI.ResultsEighty-six recipients received transplantation from 69 donors with BSI. The most common isolated pathogens from donors were Gram-positive bacteria (72.0%), followed by Gram-negative bacteria (22.7%), and fungi (5.3%). Appropriate antimicrobial agents were used in 47.8% of donors before transplantation. Transmission occurred only in 1 of 83 recipients (1.2%) from bacteremic donors and 1 of 6 recipients (16.7%) from fungemic donors. One-year patient and graft survival was 97.5%and 96.3%, respectively. There was no significant difference in graft and patient survival between patients who received organs from infected donors and noninfected donors.ConclusionUsing organs from donors with bacteremia seems to be a safe option with low transmission risk. The overall prognosis of using organs from donors with BSI is favorable.© 2022 The Korean Academy of Medical Sciences.

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