• Critical care medicine · Nov 1976

    The effect of tolazoline on right-to-left shunting via a patent ductus arteriosus in meconium aspiration syndrome.

    • D L Levin and G A Gregory.
    • Department of Pediatrics, University of California, San Francisco.
    • Crit. Care Med. 1976 Nov 1;4(6):304-7.

    AbstractSince arterial blood oxygen tensions are used in the evaluation of treatment of patients with meconium aspiration syndrome, it is important to recognize the occurrence of significant right-to-left shunting via a patent ductus arteriosus. The clinical findings, evidence of right-to-left ductus shunting, and outcome in eight patients with meconium aspiration syndrome are presented. Administration of tolazoline HCl and curare produced a beneficial effect on their PaO2 values.

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