• Blood Transfus · Jul 2020

    Multicenter Study Clinical Trial Observational Study

    Peri-operative blood transfusion in elective major surgery: incidence, indications and outcome - an observational multicentre study.

    • Dilek Unal, Yesim Senayli, Reyhan Polat, Donat R Spahn, Fevzı Toraman, Neslıhan Alkis, Turkish Society of Anaesthesiology and Reanimation Patient Blood Management Group, Turkish National Perioperative Transfusion Study Investigators, Alanoglu Zekeriyya, Aydinli Bahar, Bermede Ahmet Onat, Bilgin Hulya, Buget Mehmet, Coskunfirat Nesil, Demir Asli, Goren Suna, Guner Can Meltem, Orhan Mukadder, Senturk Mert, Tezcan Busra, Toprak Huseyin Ilksen, Yildirim Guclu Cigdem, Abitagaoglu Suheyla, Abut Yesim, Akdaglı Ekici Arzu, Akdas Tekin Esra, Akdogan Ali, Akin Mine, Akovali Nukhet, Aksoy Semsi Mustafa, Alaygut Ergin, Arar Makbule Cavidan, Arican Sule, Arici Ayse Gulbin, Arik Emine, Arik Esma, Arslan Mahmut, Ay Necmiye, Aykac Zuhal, Ayoglu Hilal, Basaran Cumhur, Baytas Volkan, Bedirli Nurdan, Bestas Azize, Bigat Zekiye, Bilgin Mehmet Ugur, Boran Omer Faruk, Buyukcoban Sibel, Cakar Turhan Sanem, Cakmak Meltem, Cankaya Baris, Capar Ayse, Cebeci Zubeyir, Cetinkaya Ethemoglu Filiz Banu, Cicekci Faruk, Colak Alkin, Colak Yusuf Ziya, Dagli Esra, Demir Hafize Fisun, Derbent Abdurrahim, Dumanlı Ozcan Ayca, Ekinci Osman, Erdogan Kayhan Gulay, Erturk Engin, Erus Ipek, Esen Tekeli Arzu, Gamli Mehmet, Gulel Basak, Gulgun Gamze, Gunduz Emel, Gunes Isin, Guven Aytac Betul, Hacibeyoglu Gulcin, Has Selmi Nazan, Ilgaz Kocyigit Ozgen, Ilksen Egilmez Ayse, Iyigun Muzeyyen, Kara Inci, Karakaya Deniz, Karasu Derya, Karaveli Arzu, Kavas Ayse Duygu, Kaya Mensure, Kaya Suleyman, Kazak Bengisun Zuleyha, Keskin Gulsen, Kilci Oya, Kilic Yeliz, Kirdemir Pakize, Koc Zeynep, Koksal Ceren, Kozanhan Betul, Kucukguclu Semih, Kucukosman Gamze, Kupeli Ilke, Kurtay Aysun, Kurtipek Omer, Meco Basak Ceyda, Nalbant Burak, Okyay Rahsan Dilek, Omur Dilek, Orak Yavuz, Ounde Elif, Özayar Esra, Ozcelik Menekse, Ozden Eyup Sabri, Ozer Yetkin, Ozgok Aysegul, Ozhan Mehmet Ozgur, Ozlu Onur, Sagir Ozlem, Saglik Arzu, Sagun Aslinur, Sahap Mehmet, Sahin Cihan, Sahiner Yeliz, Salman Nevriye, Saracoglu Ayten, Saracoglu Kemal Tolga, Sarizeybek Hilal, Selcuk Sert Gokce, Sen Betul, Sen Ozlem, Sener Elif Bengi, Sengul Fatma Isil, Silay Emin, Subası Ferhunde Dilek, Tarikci Kilic Ebru, Tas Nilay, Tekgul Zeki Tuncel, Tekgunduz Sibel, Tezcan Keles Gonul, Topcu Hulya, Tunay Abdurrahman, Ugun Fatih, Un Canan, Unal Petek, Unver Suheyla, Ural Sedef Gulcin, Uzumcugil Filiz, Yerebakan Akesen Selcan, Yesildal Kadir, Yildirim Mustafa, Yildiz Altun Aysun, Yildiz Munise, Yilmaz Erisen Hatice, Yilmaz Hakan, Yilmaz Mehmet, and Yuzkat Nureddin.
    • Department of Anaesthesiology and Reanimation, University of Health Sciences Diskapi Yildirim Beyazit Teaching Hospital, Ankara, Turkey.
    • Blood Transfus. 2020 Jul 1; 18 (4): 261-279.

    BackgroundPatients' demographic and epidemiological characteristics, local variations in clinicians' knowledge and experience and types of surgery can influence peri-operative transfusion practices. Sharing data on transfusion practices and recipients may improve patients' care and implementation of Patient Blood Management (PBM).Materials And MethodsThis was a multicentre, prospective, observational, cross-sectional study that included 61 centres. Clinical and transfusion data of patients undergoing major elective surgery were collected; transfusion predictors and patients' outcomes were analysed.ResultsOf 6,121 patients, 1,579 (25.8%) received a peri-operative transfusion. A total of 5,812 blood components were transfused: red blood cells (RBC), fresh-frozen plasma and platelets in 1,425 (23.3%), 762 (12.4%) and 88 (1.4%) cases, respectively). Pre-operative anaemia was identified in 2,019 (33%) patients. Half of the RBC units were used by patients in the age group 45-69 years. Specific procedures with the highest RBC use were coronary artery bypass grafting (16.9% of all units) and hip arthroplasty (14.9%). Low haemoglobin concentration was the most common indication for intra-operative RBC transfusion (57%) and plasma and platelet transfusions were mostly initiated for acute bleeding (61.3% and 61.1%, respectively). The RBC transfusion rate in study centres varied from 2% to 72%. RBC transfusion was inappropriate in 99% (n=150/151) of pre-operative, 23% (n=211/926) of intra-operative and 43% (n=308/716) of post-operative RBC transfusion episodes. Pre-operative haemoglobin, increased blood loss, open surgery and duration of surgery were the main independent predictors of intra-operative RBC transfusion. Low pre-operative haemoglobin concentration was independently associated with post-operative pulmonary complications.ConclusionsThese findings identified areas for improvement in peri-operative transfusion practice and PBM implementation in Turkey.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…