• Milan Milovancev, Katy Townsend, Jason Spina, Connie Hurley, S Christopher Ralphs, Brian Trumpatori, Bernard Seguin, and Kieri Jermyn.
• Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, Oregon.
• Vet Surg. 2016 Jul 1; 45 (5): 577-81.

ObjectiveEvaluate the effect of a perioperative intravenous continuous rate infusion (CRI) of metoclopramide on the incidence of aspiration pneumonia in the short term postoperative period in dogs undergoing unilateral arytenoid lateralization.Study DesignProspective, randomized, multi-center clinical trial.Animals61 client-owned dogs with idiopathic laryngeal paralysis and normal preoperative thoracic radiographs.MethodsAll dogs underwent unilateral arytenoid lateralization with a uniform anesthetic, analgesic, and management protocol. Dogs in the treatment group received an intravenous CRI of metoclopramide for 24 hours perioperative. All dogs were assessed for clinical signs of aspiration pneumonia based on the results of physical examination and owner interview up to the point of suture removal (10-14 days postoperative). Any dog with suspected aspiration pneumonia had thoracic radiographs performed.ResultsSix dogs developed aspiration pneumonia in the short term postoperative period (2/28 control dogs and 4/33 treated dogs), accounting for an overall frequency of 10% with no significant difference between control and treated dogs. No variables measured in the study were significantly different between control and treated dogs.ConclusionsPerioperative metoclopramide, at the doses used in this study, did not affect the incidence of aspiration pneumonia in the short term postoperative period in dogs with idiopathic laryngeal paralysis undergoing unilateral arytenoid lateralization.© Copyright 2016 by The American College of Veterinary Surgeons.

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