• Jayakumar Sreenivasan, Sagar Ranka, Shubham Lahan, Ahmed Abu-Haniyeh, Heyi Li, Risheek Kaul, Aaqib Malik, Wilbert S Aronow, William H Frishman, and Steven Lansman.
• Department of Cardiology, Westchester Medical Center / New York Medical College, Valhalla, NY Department of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS University College of Medical Sciences, New Delhi, India Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.
• Cardiol Rev. 2021 Jul 20.

AbstractCoronavirus disease 2019 (COVID-19) is characterized by a clinical spectrum of diseases ranging from asymptomatic or mild cases to severe pneumonia with acute respiratory distress syndrome (ARDS) requiring mechanical ventilation. Extracorporeal membrane oxygenation (ECMO) has been used as rescue therapy in appropriate patients with COVID-19 complicated by ARDS refractory to mechanical ventilation. In this study, we review the indications, challenges, complications and clinical outcomes of ECMO utilization in critically ill patients with COVID-19 related ARDS. Most of these patients required venovenous ECMO. Although the risk of mortality and complications is very high among patients with COVID-19 requiring ECMO, it is similar to that of non-COVID-19 patients with ARDS requiring ECMO. ECMO is a resource-intensive therapy, with an inherent risk of complications, which makes its availability limited and its use challenging in the midst of a pandemic. Well-maintained data registries, with timely reporting of outcomes and evidence-based clinical guidelines, are necessary for the careful allocation of resources and for the development of standardized utilization protocols.Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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