• Medical hypotheses · Oct 2020

    Letter Review

    A hypothesis on the role of the human immune system in covid-19.

    • Hind Khairi Khashkhosha and Muhammed Elhadi.
    • Faculty of Medicine, University of Tripoli, Tripoli, Libya.
    • Med. Hypotheses. 2020 Oct 1; 143: 110066.

    AbstractThe COVID-19 pandemic has not spared any continent. The disease has affected more than 7,500,000 individuals globally and killed approximately 450,000 individuals. The disease is caused by a very small virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is an enveloped single-stranded RNA virus with a spike-like structure on its envelope that can interact with the angiotensin-converting enzyme 2 (ACE2) receptor after cleavage. ACE2 receptors are present in the human lungs and other organs. SARS-CoV-2 is a new virus that belongs to the subgenus Sarbecovirus; viruses in this subgenus have spread widely in the previous years and caused outbreaks of severe acute respiratory syndromes.Copyright © 2020 Elsevier Ltd. All rights reserved.

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