• Respirology · May 2014

    Survival analysis of time-to-event data in respiratory health research studies.

    • Jessica Kasza, Darren Wraith, Karen Lamb, and Rory Wolfe.
    • Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia; Victorian Centre for Biostatistics (ViCBiostat), Melbourne, Victoria, Australia.
    • Respirology. 2014 May 1; 19 (4): 483-92.

    AbstractThis article provides a review of techniques for the analysis of survival data arising from respiratory health studies. Popular techniques such as the Kaplan-Meier survival plot and the Cox proportional hazards model are presented and illustrated using data from a lung cancer study. Advanced issues are also discussed, including parametric proportional hazards models, accelerated failure time models, time-varying explanatory variables, simultaneous analysis of multiple types of outcome events and the restricted mean survival time, a novel measure of the effect of treatment. © 2014 Asian Pacific Society of Respirology.

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