• Lisa M Pollack, Jerry L Lowder, Matt Keller, Su-Hsin Chang, Sarah J Gehlert, and Margaret A Olsen.
• Division of Public Health Sciences, Department of Surgery (Drs. Pollack, Chang, Gehlert, and Olsen); Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology (Dr. Lowder); Division of Infectious Diseases, Department of Medicine (Dr. Olsen and Mr. Keller), Washington University School of Medicine in St. Louis; Department of Public Health-Social Work, George Warren Brown School of Social Work, Washington University in St. Louis (Dr. Gehlert), St. Louis, Missouri; Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, California (Dr. Gehlert). Electronic address: lpollack@wustl.edu.
• J Minim Invasive Gynecol. 2021 May 1; 28 (5): 1022-1032.e12.

Study ObjectiveEvaluate whether 30- and 90-day surgical complication and postoperative hospitalization rates after hysterectomy for benign conditions differ by race/ethnicity and whether the differences remain after controlling for patient, hospital, and surgical characteristics.DesignRetrospective cohort study using administrative data. The exposure was race/ethnicity. The outcomes included 5 different surgical complications/categories and posthysterectomy inpatient hospitalization, all identified through 30 and 90 days after hysterectomy hospital discharge, with the exception of hemorrhage/hematoma, which was only identified through 30 days. To examine the association between race/ethnicity and each outcome, we used logistic regression with clustering of procedures within hospitals, adjusting for patient and hospital characteristics and surgical approach.SettingMultistate, including Florida and New York.PatientsWomen aged ≥18 years who underwent hysterectomy for benign conditions using State Inpatient Databases and State Ambulatory Surgery Databases.InterventionsHysterectomy for benign conditions.Measurements And Main ResultsWe included 183 697 women undergoing hysterectomy for benign conditions from January 2011 to September 2014. In analysis, adjusting for surgery route and other factors, black race was associated with increased risk of 30-day digestive system complications (multivariable adjusted odds ratio [aOR], 1.98; 95% confidence interval [CI], 1.78-2.21), surgical-site infection (aOR, 1.34; 95% CI, 1.18-1.53), posthysterectomy hospitalization (aOR, 1.31; 95% CI, 1.22-1.40), and urologic complications (aOR, 1.16; 95% CI, 1.01-1.34) compared with white race. Asian/Pacific Islander race was associated with increased risk of 30-day urologic complications (aOR, 1.48; 95% CI, 1.08-2.03), intraoperative injury to abdominal/pelvic organs (aOR, 1.46; 95% CI, 1.23-1.75), and hemorrhage/hematoma (aOR, 1.33; 95% CI, 1.06-1.67) compared with white race. Hispanic ethnicity was associated with increased risk of 30-day posthysterectomy hospitalization (aOR, 1.11; 95% CI, 1.02-1.20) compared with white race. All findings were similar at 90 days.ConclusionBlack and Asian/Pacific Islander women had higher risk of some 30- and 90-day surgical complications after hysterectomy than white women. Black and Hispanic women had higher risk of posthysterectomy hospitalization. Intervention strategies aimed at identifying and better managing disparities in pre-existing conditions/comorbidities could reduce racial/ethnic differences in outcomes.Copyright © 2021 AAGL. Published by Elsevier Inc. All rights reserved.

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