• La Tunisie médicale · Jul 2015

    Review

    [Medical treatment of endometriosis].

    • Sadok Derouich, Leila Attia, Olfa Slimani, Arij Bouzid, Nabil Mathlouthi, Riadh Ben Temim, and Tahar Makhlouf.
    • Tunis Med. 2015 Jul 1; 93 (7): 407-12.

    PrerequisitesPathogenesis and pathophysiology of endometriosis, pharmacodynamics of oral contraceptives, progestagens, antiprogestagens, danazol, GnRh agonist and non-steroidal antiinflammatory.Purpose Of ReviewThe aim of this paper is to systematically review the literature evidence of medical treatments for endometriosis and to summarize recently published recommendations.MethodsLiterature and recently published recommendations review via bibliographic research using Pubmed/Medline, Google scholar and Cochrane database.ResultsEndometriosis is an estrogen-dependent gynecological disease. Medical treatement of endometriosis induce an estrogen deprivation situation. The Oral contraceptives reduce the rate of postoperative endometrioma recurrence and should be considered an essential part of long-term therapeutic strategies.New agents promise a distinct perspective in endometriosis treatment.ConclusionsThe effectiveness of medical treatmentis well established in the management pelvic pain and infertility associated with endometriosis and constitutes an important alternative or complement to surgery.

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