• Merrick Miles, Bret D Alvis, Kyle Hocking, Franz Baudenbacher, Christy Guth, Joann Lindenfeld, Colleen Brophy, and Susan Eagle.
• Vanderbilt University Medical Center, Department of Anesthesiology, Division of Critical Care, Nashville, Tennessee.
• J. Card. Fail. 2018 Aug 1; 24 (8): 525-532.

BackgroundTo determine the feasibility of peripheral intravenous volume analysis (PIVA) of venous waveforms for assessing volume overload in patients admitted to the hospital with acute decompensated heart failure (ADHF).MethodsVenous waveforms were captured from a peripheral intravenous catheter in subjects admitted for ADHF and healthy age-matched controls. Admission PIVA signal, brain natriuretic peptide, and chest radiographic measurements were related to the net volume removed during diuresis.ResultsADHF patients had a significantly greater PIVA signal on admission compared with the control group (P = .0013, n = 18). At discharge, ADHF patients had a PIVA signal similar to the control group. PIVA signal, not brain natriuretic peptide or chest radiographic measures, accurately predicted the amount of volume removed during diuresis (R2 = 0.781, n = 14). PIVA signal at time of discharge greater than 0.20, demonstrated 83.3% 120-day readmission rate.ConclusionsThis study demonstrates the feasibility of PIVA for assessment of volume overload in patients admitted to the hospital with ADHF.Copyright © 2018 Elsevier Inc. All rights reserved.

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