• Br J Anaesth · Mar 2022

    Editorial Comment

    Buprenorphine: a treatment and cause of opioid-induced respiratory depression.

    • Albert Dahan, Maarten van Lemmen, Simone Jansen, Pieter Simons, and Rutger van der Schrier.
    • Department of Anesthesiology, Anesthesia & Pain Research Unit, Leiden University Medical Center, Leiden, the Netherlands. Electronic address: a.dahan@lumc.nl.
    • Br J Anaesth. 2022 Mar 1; 128 (3): 402-404.

    AbstractBuprenorphine is a partial agonist at the mu opioid receptor. Due to its relatively low maximum effect on respiratory depression it is considered by some to be a safe opioid. But it can produce serious respiratory depression, particularly when combined with sedatives such as benzodiazepines.Copyright © 2021 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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