• Stephanie Baltaji, Erica Rabold, Lamé Balikani, Timothy Mickus, and Sohini Ghosh.
• Department of Pulmonary and Critical Care Medicine, Allegheny Health Network, Pittsburgh, PA.
• Chest. 2021 Nov 1; 160 (5): e523-e526.

Case PresentationA 57-year-old man with history of stage IIIB right-sided malignant pleural mesothelioma was admitted from his oncologist's office for progressive dyspnea of two weeks duration. He had associated dyspnea at rest and a new dry cough. He denied sputum production, hemoptysis, or fevers, but he did endorse chills, fatigue, and weight loss. The patient was a veteran of the Navy and had extensive international travel in his 20s. He had never been incarcerated and denied any sick contacts or recent travels. He had received a diagnosis of mesothelioma 11 months earlier after presenting to his physician's office with complaints of shortness of breath on exertion. Initial imaging revealed a large right-sided pleural effusion with irregular pleural thickening. He underwent right-sided thoracoscopy, and the pleural biopsy result was consistent with epithelioid mesothelioma. Because of invasion of his seventh rib, he was not a candidate for surgery and underwent palliative radiation and chemotherapy with cisplatin, pemetrexed, and bevacizumab. He was undergoing his eighth cycle of chemotherapy at the time of presentation.Copyright © 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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