• Chest · Feb 2022

    Prevalence, Deaths, and Disability-Adjusted Life-Years Resulting from Asthma and Its Attributable Risk Factors in 204 Countries and Territories, 1990-2019.

    • Saeid Safiri, Kristin Carson-Chahhoud, Nahid Karamzad, SullmanMark J MMJMDepartment of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus; Department of Social Sciences, University of Nicosia, Nicosia, Cyprus., Seyed Aria Nejadghaderi, Ali Taghizadieh, Arielle Wilder Bell, Ali-Asghar Kolahi, Khalil Ansarin, Mohammad Ali Mansournia, Gary S Collins, and Jay S Kaufman.
    • Tuberculosis and Lung Disease Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Tehran, Iran; Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Tehran, Iran. Electronic address: safiris@tbzmed.ac.ir.
    • Chest. 2022 Feb 1; 161 (2): 318329318-329.

    BackgroundUnderstanding global trends in the point prevalence, deaths, and disability-adjusted life-years (DALYs) for asthma will facilitate evidence-based decision-making.Research QuestionWhat are the global, regional, and national burdens of asthma in 204 countries and territories between 1990 and 2019 by age, sex, and sociodemographic index (SDI)?Study Design And MethodsPublicly available data from the Global Burden of Disease study from 1990 through 2019 were used. All estimates were presented as counts and age-standardized rates per 100,000, along with their associated uncertainty intervals.ResultsIn 2019, the global age-standardized point prevalence and death rates for asthma were 3,415.5 and 5.8 per 100,000, which represent a 24% and 51.3% decrease since 1990, respectively. Moreover, in 2019, the global age-standardized DALY rate was 273.6 and the global point prevalence of asthma was highest in the group 5 to 9 years of age. Also in 2019, the United States (10,399.3) showed the highest age-standardized point prevalence rate of asthma. Generally, the burden of asthma decreased with increasing SDI. Globally, high BMI (16.9%), smoking (9.9%), and occupational asthmagens (8.8%) contributed to the 2019 asthma DALYs.InterpretationAsthma remains an important public health issue, particularly in regions with low socioeconomic development. Future research is needed to examine thoroughly the associations asthma has with its risk factors and the factors impeding optimal self-management. Further research also is needed to understand and implement better the interventions that have reduced the burden of asthma.Copyright © 2021 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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