• Internal medicine · Aug 2022

    Case Reports

    A Case of Bilateral Inflammatory Breast Cancer that Developed Two Years after Treatment for Triple-negative Breast Cancer1.

    • Yuta Kawaguchi, Sayaka Kuba, Michi Morita, Xiangyue Meng, Hiroko Hayashi, Kazuma Kobayashi, Tomohiko Adachi, Masaaki Hidaka, Shinichiro Itoh, Kengo Kanetaka, and Susumu Eguchi.
    • Department of Surgery, Yamaguchi Prefectural Grand Medical Center, Japan.
    • Intern. Med. 2022 Aug 1; 61 (15): 2387-2391.

    AbstractA 66-year-old woman underwent partial mastectomy and a sentinel lymph node biopsy for left breast cancer; the pathological diagnosis was invasive ductal carcinoma (pT1aN0, pStage I, triple-negative subtype). Postoperative radiotherapy was performed. Two years later, she developed redness and induration at both breasts. The diagnosis was bilateral inflammatory breast cancer. After four cycles of dose-dense epirubicin and cyclophosphamide followed by 12 weekly paclitaxel cycles, bilateral total mastectomy and axillary lymph node dissection were performed. At the one-year follow-up after undergoing operation and radiotherapy, she remained alive without recurrence. Dose-dense treatment regimens may help patients achieve complete resection without short-term recurrence.

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