• Zhi-Tao Feng, Da-Shi Ying, Zhan-Shuang Qiu, Tie Li, Xiao-Ru Xu, Ji-Yu Yang, and Zhi-Hong Wang.
• Changchun University of Traditional Chinese Medicine, College of Acupuncture and Tuina, P.R. China.
• Medicine (Baltimore). 2021 Dec 3; 100 (48): e28037.

BackgroundInsomnia is characterized by high incidence, easy recurrence, and difficulty in curing. Serious insomnia not only seriously affects the body organ function but also causes great damage psychological.Umbilical acupuncture (UA) has fewer side effects and is increasingly used to treat insomnia. This study aimed to systematically review the effectiveness and safety of UA in the treatment of insomnia.MethodsLiterature on UA for insomnia in PubMed, Excerpt Medica Database, the Cochrane Central Register of Controlled Trials, Web of Science, China National Knowledge Infrastructure Database, China Biomedical Literature Database, Chinese Scientific Journal Database, and Wan Fang Database were searched from the creation of these databases to October 3, 2021. In addition, the reference lists of studies meeting the inclusion criteria will also be searched to achieve a comprehensive retrieval of the maximum. All randomized controlled trials of UA for treating insomnia were included. Two reviewers will conduct literature screening, data extraction, and quality evaluation respectively. The main outcome was the Pittsburgh Sleep Quality Index, and the secondary outcomes included clinical efficacy, and safety. RevMan 5.4.1 software was used for mate analysis.ResultsThis study aimed to evaluate the current status of UA treatment for insomnia, with the aim of illustrating the effectiveness and safety of UA.ConclusionThis study will provides a high-quality evidence to evaluate the effectiveness and safety of UA in treating insomnia.RegistrationPROSPERO CRD42021283036.Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc.

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