• Atencion primaria · Mar 2022

    Review Meta Analysis

    [Treatment of scabies].

    • Daniel Morgado-Carrasco, Jaime Piquero-Casals, and Sebastian Podlipnik.
    • Servicio de Dermatología, Hospital de Figueres, Fundació Salut Empordà, Figueres, Girona, España; Servicio de Dermatología, Hospital Clínic de Barcelona, Universitat de Barcelona, Barcelona, España. Electronic address: morgadodaniel8@gmail.com.
    • Aten Primaria. 2022 Mar 1; 54 (3): 102231.

    AbstractScabies affects more than 200 million people around the world, and causes a significant socioeconomic impact. Prolonged skin-to-skin contact is the primary mode of transmission. Fomite-mediated transmission is uncommon, although it can be significant in crusted scabies. Topical therapy with permethrin 5% is recommended as first-line treatment. It can be indicated during pregnancy and lactation, and appears to be safe in children <2 months. However, a decrease in the effectiveness of this drug has recently been reported. Another first-line therapeutic alternative is oral ivermectin. It can be administered during lactation, and new evidence suggests that it is safe in children >15kg. Diverse systematic reviews and meta-analysis have concluded that oral ivermectin is as effective and safe as topical permethrin. Mass drug administration of oral ivermectin is an excellent option for the management of scabies in communities with high prevalence, or for scabies outbreaks in institutions.Copyright © 2021 The Authors. Publicado por Elsevier España, S.L.U. All rights reserved.

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