• Sang Hoon Lee, Hyun Hee Choi, and Min Cheol Chang.
• Department of Radiology, Madi Pain Management Center, Jeonju, Republic of Korea.
• Pain Physician. 2022 Jan 1; 25 (1): E141-E145.

BackgroundNeuropathic pain in the hands due to carpal tunnel syndrome (CTS) disturbs sleep and affects the quality of life.ObjectivesWe evaluated the effect of ultrasound (US)-guided partial release of the transverse carpal ligament (TCL) using an 18-G needle in patients with refractory CTS.Study DesignA prospective outcome study.SettingThe outpatient clinic of a single academic medical center.MethodsThis study was prospectively conducted. A total of 155 consecutive patients (191 wrists) with refractory chronic CTS (M:F = 28:127; age = 54.7 ± 9.6 years; pain duration = 50.3 ± 36.3 weeks) were enrolled and underwent US-guided partial release of the TCL using a needle. The pain severity was measured using the Numeric Rating Scale (NRS) at 3 and 6 months after the treatment. Successful treatment outcomes were defined as more than 50% reduction in the NRS score at 6 months after the treatment compared with the score at pre-treatment and NRS score < 3 at 6 months after the treatment without any surgical intervention.ResultsThere were 3 dropouts, and 188 wrists were included in the study. No side effects were reported. A total of 162 wrists (86.2%) showed successful treatment outcomes at 6 months after TCL release. Of the 26 wrists which had unsuccessful treatment outcomes, 6 received surgical treatment. The NRS scores at 3- and 6-month post-treatment were significantly reduced: the average NRS scores were 7.1 ± 0.6 at baseline, 1.9 ± 1.7 at 3 months after the treatment, and 1.7 ± 1.7 at 6 months after the treatment.LimitationsWe conducted our study without a control or a placebo group.ConclusionWe believe that US-guided partial release of the TCL using a needle can be an effective and safe technique for treating chronic refractory pain due to CTS. It can potentially be attempted before surgical treatment.

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